Longevity drugs
Does rapamycin slow aging in humans?
Rapamycin has unusually strong aging-biology interest, but it is not proven to slow human aging or extend lifespan in healthy adults.
Evidence:Human trial evidenceRisk:High riskStatus:Off-label
Longevity health claims, checked against the evidence
Plain-English checks of anti-aging drugs, peptides, supplements, tests and treatments—without turning early science into a promise.
Simple answer
Many longevity health claims start with real biology, then overstate what has been proved in people. Use these checks to separate a plausible mechanism or biomarker from evidence of meaningful human benefit, while keeping risk and approval status visible.
This index covers health and anti-aging claims—not unverified claims about people living to extreme ages.
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Longevity drugs
Does metformin extend lifespan in healthy non-diabetic adults?
Metformin is an important diabetes drug and longevity candidate, but it is not proven to extend lifespan in healthy non-diabetic adults.
Evidence:Human observational evidenceRisk:Moderate riskStatus:Off-label
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