[LHN]

Explore longevity topics

Choose what you heard about, then start with plain-English answers before going deeper into the evidence.

New to all of this?

Start with the five questions that make any longevity claim easier to read.

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Heard a specific claim?

Search the claim index for a simple answer first, then open evidence only if needed.

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Worried about peptide status?

Open the FDA peptide tracker for approval and compounding context.

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Peptides

BPC-157, TB-500, KPV, MOTS-c, GHK-Cu, Semax, Epitalon, CJC-1295, Ipamorelin, Sermorelin and the messy line between approved medicine, compounding and research chemicals.

Longevity Drugs

Rapamycin, metformin, acarbose, GLP-1s, SGLT2 inhibitors and other drugs discussed as geroprotectors.

NAD, Supplements & Mitochondria

NMN, NR, NAD IV, urolithin A, taurine, creatine, CoQ10, spermidine, resveratrol, berberine and mitochondrial health claims.

Gene Therapy & Reprogramming

CRISPR, FDA-approved gene therapies, partial epigenetic reprogramming, OSK factors, ER-100, telomerase and the frontier of cellular rejuvenation.

Biological Age & Biomarkers

Epigenetic clocks, biological age tests, VO2 max, DEXA, CGM, ApoB, Lp(a), HRV, blood panels and quantified-self measurement.

Senolytics & Cellular Aging

Senescent cells, senolytics, fisetin, quercetin, dasatinib, inflammation, immune aging and the hallmarks of aging.

Performance, Recovery & Lifestyle

Exercise, sleep, sauna, cold exposure, fasting, protein, strength training, zone 2, VO2 max and recovery basics.

Regulation, Safety & Clinics

FDA status, compounding, off-label use, supplement claims, longevity clinics, med spas, advertising claims, source quality and patient safety.