Drug
Rapamycin
Also known as: Sirolimus
Plain-English definition
An mTOR-inhibiting drug discussed as a geroscience candidate.
Why it matters
It has serious aging-biology interest but off-label longevity use is medically sensitive.
Status summary
Approved for specific medical uses, not for human longevity.
Evidence summary
Promising biology and animal data; human aging endpoints remain unproven.
Source links
- PubMed search: rapamycin aging humans - PubMed
Source-discovery link for primary literature and reviews.
- ClinicalTrials.gov search: rapamycin aging - ClinicalTrials.gov
Trial registry link for registered human studies.
Related claim checks
Longevity drugs
Does rapamycin slow aging in humans?
Rapamycin has unusually strong aging-biology interest, but it is not proven to slow human aging or extend lifespan in healthy adults.
Related articles
Guide
Does rapamycin slow aging in humans?
Rapamycin is one of the most discussed geroscience drugs, but human longevity evidence remains incomplete.
Guide
What did the PEARL rapamycin trial actually show?
PEARL is important because it asks human questions, but readers should distinguish trial signals from sweeping longevity claims.