Human Rct
Controlled human trial evidence. We still check sample size, endpoints, population and replication.
Evidence grading method
LHN separates evidence type from claim strength. A human RCT can still be too small or too indirect for a broad longevity claim, and a mechanism can be important without proving a consumer outcome.
Human Observational
Human association data. Useful for signals, weaker for causal claims.
Clinical Trial Registered
A trial exists or is registered. Registration is not proof of benefit.
Animal Preclinical
Animal evidence. Important for biology, not enough for human consumer claims by itself.
Mechanism Only
Mechanistic plausibility without direct human outcome evidence.
Anecdotal Social
User reports or forum discussion. Useful as demand signal, not evidence of efficacy.
Regulatory Signal
Agency action, label, warning, meeting or registry signal.
Commercial Claim
A product, clinic or marketing claim that needs independent verification.
Unknown
Insufficient source clarity to classify confidently.