[LHN]

Clinical trials tracker

Registry-aware watchpoints for longevity-relevant human studies. Trial registration is evidence of a question, not proof of an answer.

Longevity drugs

ItemClaimsStatusEvidence / riskSource
Rapamycin / sirolimus aging studies

Checked 2026-06-27

Related briefing
mTOR modulation, immune aging, biological ageCheck each registry entry for status and endpoints
Evidence:Trial registeredRisk:High riskStatus:Off-label

Human trials are important but vary widely in design, population and outcome strength.

Prescription-drug adverse effects, infection risk, monitoring burden.

ClinicalTrials.gov
Metformin aging-related trials

Checked 2026-06-27

Related briefing
geroscience, multimorbidity delay, metabolic resilienceApproved for other uses; aging endpoints remain under study
Evidence:Trial registeredRisk:Moderate riskStatus:Approved for another use

The key question is whether metformin affects aging-related outcomes beyond diabetes treatment.

Medication interactions, kidney considerations, inappropriate use.

ClinicalTrials.gov

Senolytics

ItemClaimsStatusEvidence / riskSource
Senolytic trials

Checked 2026-06-27

Related briefing
senescent-cell reduction, frailty, tissue functionDisease- and trial-specific; not broad consumer use
Evidence:Trial registeredRisk:High riskStatus:Experimental

Human work is emerging, but consumer longevity claims remain ahead of outcomes.

Drug toxicity, inappropriate combinations, weak biomarker interpretation.

ClinicalTrials.gov